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Boosting solid state chemical reactions

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Ralph Elliot
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Adding olefin enables efficient solvent-free cross-coupling reactions, leading to environmentally friendly syntheses of a wide range of organic materials.

A cross coupling reaction is typically performed in an organic solvent and leads to the production of a large amount of solvent waste, which is often harmful to the environment.

A new strategy developed by Hokkaido University researchers in Japan opens the door for more environmentally friendly solvent-free solid-state cross coupling processes using mechanochemistry.

It also has many potential applications, including the development of organic materials found in solar cells and light-emitting diodes.

Cross-coupling reactions proceed efficiently in the presence of a metal catalyst to form a wide range of organic molecules with novel properties.

In particular, the Nobel-prize-winning palladium-catalysed cross-coupling reactions have long been used in the synthesis of natural products, in medicinal chemistry, and in polymer and materials science.

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Ralph Elliot
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