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Researchers unlock the biomechanics of how the Ebola virus attaches to its host cell

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Dion Esparza
Mar 26, 2019 18:41
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Those infected with the Ebola virus experience severe illness, including hemorrhagic fever, which can lead to internal bleeding.

According to the U.S. Centers for Disease Control and Prevention (CDC), currently, there is no specific medical treatment for Ebola.

Scientists know that to enter a human cell, Ebola takes advantage of a natural process called macropinocytosis, through which the cell "cleans up" its surroundings by internalizing the dead cell debris that surrounds it.

Once inside, the Ebola virus membrane fuses to the endosome that has formed around it and releases its genetic content into the cell.

"Viral RNA further hijacks the cell mechanism to make proteins and replicate themselves inside.

Then they bud off the membrane to form a new virus while the healthy host cell dies," says (Frank Zhang, associate professor of bioengineering and of mechanical engineering at Lehigh University (https://www1.lehigh.edu/).

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Dion Esparza
Mar 26, 2019 18:41
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