A joint team of scientists from Russia and the United States designed a method for marking dividing stem cells with three different labels.
The new method will increase the accuracy and speed of stem cell division analysis and reveal new populations of stem cells.
The research team, led by Grigori Enikolopov, was made up of specialists from the Moscow Institute of Physics and Technology (MIPT), Stony Brook University (USA), Cold Spring Harbor Laboratory (USA), and Koltzov Institute of Developmental Biology of the Russian Academy of Sciences.
Usually, tissue regeneration proceeds in the following manner: After stem cells duplicate themselves, some of their offspring are used to restock the supply of stem cells, and some convert into other types of cells in order to repair the loss or damage.
What the scientists aim to discover are the mechanisms common to all types of stem cells and the ways they can be influenced or improved.
As a stem cell duplicates itself, it goes through a stage called the S phase (see fig.