logo
logo

Imaging individual flexible DNA 'building blocks' in 3-D

avatar
Bob Sun
img

Over the past decade, researchers have been working to create nanoscale materials and devices using DNA as construction materials through a process called "DNA origami."

A single long "scaffold" strand of DNA can be folded into specific shapes by hundreds of shorter strands, for example.

Scientists hope to use this method to develop molecular devices that function as nanoscale machines or drug-delivery devices, markers for medical imaging or biological research, and components for electronic devices.

Long DNA scaffolds - composed of more than 10,000 DNA structural units called "nucleotides" - have remained difficult to manufacture and manipulate, which has so far limited the size of origami structures.

The methods used here could easily be applied to other types of fabricated DNA origami structures, and help inform the design and optimization of future structures.

Their work was recently published in Nature Communications.

collect
0
avatar
Bob Sun
guide
Zupyak is a free content platform for publishing and discovering stories, software and startups.