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Merge attack: Scientists find mechanism of virus penetration into living cell

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Gladys Wiggins
Jul 30, 2018 16:16
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Frumkin Institute of Physical Chemistry & Electrochemistry (RAS), NUST MISIS, and MIPT, as well as participants from several other research centers, have described the biophysical principles of influenza's infiltration into the body's cells.

The researchers have created a theoretical model describing the mechanical properties of the lipid membranes of both the virus and the targeted cells, making it possible to connect the mechanisms of membranes with cell resistance.

Viruses often present the main threat to the human body, with diseases like Human Immunodeficiency Virus (HIV), Herpes, Hepatitis, Ebola and forms of influenza, among others, causing serious damage.

These viruses invade the cells of the affected body by merging their membrane with the cell membrane or its organelles.

Because of this unusual mechanism of penetration, it turned out that the viral infection process of cells often depends on the properties of the cell's lipid membrane, particularly its elasticity.

In other words, the more difficult it is for viral proteins to mechanically deform the cell membrane, the less likely it is that the cell will be infected.

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Gladys Wiggins
Jul 30, 2018 16:16
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