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New test measures men's fertility

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Dennis Colella
Oct 24, 2018 21:20
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ITHACA, N.Y. - At a time when more than half of male infertility cannot be explained by current methods, a new test developed by Androvia LifeSciences is able to measure male fertility.

The proprietary Cap-Score Male Fertility Assay is based on research patented by the Travis lab at the Baker Institute for Animal Health and Cornell University's College of Veterinary Medicine and was recently the subject of a study that appeared Sept. 24 in the journal Molecular Reproduction and Development.

"Out of all the tests commonly used to measure sperm, the Cap-Score is the only one that prospectively has been shown to indicate the probability of a man to generate a pregnancy," said Dr. Alexander Travis, professor of reproductive biology in the Department of Biomedical Sciences, director of Cornell's new Master of Public Health program, as well as Androvia's co-founder and chief scientific officer.

Its descriptive nature fails to explain the causes of infertility or predict whether sperm will actually fertilize an egg.

The Cap-Score, on the other hand, quantifies "capacitation," the changes that take place within a sperm cell that enable it to fertilize.

Travis was the first to identify ganglioside GM1 as a biomarker for a sperm's capacitation status.

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Dennis Colella
Oct 24, 2018 21:20
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