Sports concussions, Parkinson's disease, and hormone therapy for cancer - all can have memory loss as symptoms.
Rong Xu, PhD, recently received a total of $5 million for two projects that will use big data methods for a comprehensive look at a range of factors that may inform the mechanism of Alzheimer's and related dementia.
"Vast amounts of data from seemingly unrelated sources present opportunities to researchers who aim to extract information that would help develop drugs or treatments," Says Xu, "This is especially true for diseases and conditions that may involve multiple genetic variations and that also have social or environmental influences."
These will be used to build large-scale, integrated knowledge bases related to Alzheimer's and other neurodegenerative diseases.
Through complex calculations, Xu will rank and prioritize relevant findings.
Altogether, this large-scale knowledge base will set the foundation to understand the mechanisms of disease, and to identify ways to develop new or reuse existing drugs.