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Walter Winkel 2021-07-27
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Face-morphing adult content creator Coconut Kitty is ushering in the unsettling future of the medium, one where nothing is as it seems.
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Walter Winkel 2021-05-29
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Welcome back to The TechCrunch Exchange, a weekly startups-and-markets newsletter for your weekend enjoyment.
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Walter Winkel 2021-03-26
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Women are much more likely than men to suffer from long Covid – where a host of debilitating symptoms last beyond four weeks, sometimes for more than a year. But the reason why this is the case hasn’t been made clear. 

Data from the Office for National Statistics (ONS) has repeatedly shown women tend to fare less well than men. And now, two new studies have shed more light on the gender disparities between those blighted by long-term symptoms of the virus and those who recover fairly quickly.

The first looked at the long-term effects of Covid-19 after hospital admission – 327 patients were discharged and followed up on to see how they recovered. Women under 50 had higher odds of worse long-term health outcomes when compared to men and older study participants.

Dr Janet Scott, lead author of the pre-print study, from the University of Glasgow-MRC Centre for Virus Research, said the finding could have “profound implications” for pandemic policy decision, as well as vaccination strategy.

Females under the age of 50 were five times less likely to report feeling fully recovered. They were twice as likely to report worse fatigue, seven times more likely to be breathless and more likely to have worsening difficulties or new disabilities than men of the same age.

A separate pre-print study looking at the impact of coronavirus on physical and mental health in adults discharged from hospital after having Covid-19 also found women were more impacted.

Patients were assessed between two and seven months later to see how they’d recovered. Factors associated with failure to recover included: being female, middle-aged, white ethnicity, having two or more underlying health issues, and having more severe acute illness from Covid.

Gender differences have been apparent since the start of the pandemic, when men were found to have more severe outcomes from Covid-19. They’re more likely to be hospitalised by the virus and end up in intensive care, and also twice as likely to die from the virus as women.

“We’ve appreciated throughout that there are gender differences in immunity to this virus,” Professor Daniel Altmann, of the Department of Immunology and Inflammation at Imperial College London, tells HuffPost UK. 

“In our data, women tend to have higher levels of antibody, while men tend to have higher levels of T-cell mediated immunity. As is now well appreciated, men tend to fare worse during severe, acute infection. That leaves the question of why women should be more susceptible to long Covid.”

The answer might lie in differences in how our immune systems work – or that’s what scientists hypothesise, anyway. Research is needed to look into this.

Dr Louise Newson, a GP and menopause specialist, previously said during a webinar that women have “a stronger response to infections, but especially to viruses, compared to men”. This is because women have different immune systems. She added that “frustratingly, so much research on immunity and in general is done in men and not in women”.

In a 2016 review on the differences in immune responses between males and females, professor Sabra Klein, of The Johns Hopkins Bloomberg School of Public Health, and professor Katie Flanagan, of Monash University, said females’ strong immune responses result in faster clearance of pathogens and greater vaccine efficacy compared to males. But it also contributes to females’ increased susceptibility to inflammatory and autoimmune diseases.

The sex hormone oestrogen could also play a role. A study by King’s College London (KCL) found post-menopausal women with lower levels of oestrogen appeared to be at higher risk of developing serious complications of Covid. 

The hormone, which declines in women as they age, interacts with the immune system in various ways, including influencing how many immune cells are produced and how they respond to infection.

Prof Altmann and others are looking at underpinning immune mechanisms that might explain the differences in how people recover from the virus – including the role of sex hormones. He points out women are more impacted by autoimmune diseases such as lupus and multiple sclerosis, which was “always taken to indicate interaction between sex hormones and the immune system”.

The interaction between sex hormones and the immune system now needs to feed into our thinking about long Covid, adds Prof Altmann. 

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Walter Winkel 2020-09-10
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"Vulnerability disclosures do take very weird turns from time to time"

The post TERF Wars, “Random Twitter People” and Responsible Disclosure appeared first on Computer Business Review.

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Walter Winkel 2021-07-18
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The secret to getting cheap razors? Buy them online and have them delivered on a schedule.
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Walter Winkel 2021-05-13
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Reddit is building an in-house creative strategy agency, KarmaLab, in a broader bid in recent years to grow its ads business.

The post ‘Bridge the gap between paid and organic’: Why Reddit is building an in-house agency to work with brands appeared first on Digiday.

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Walter Winkel 2021-02-25
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A State Department spokesperson told Vice that the US complained to China after learning some diplomatic staff had been made to do anal swab tests.
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Walter Winkel 2020-09-03
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Genre-bending series like I May Destroy You and Lovecraft Country may be rooted in pain, but they’re also thrillingly hopeful.
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Walter Winkel 2021-07-12
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New Zealand comedy Wellington Paranormal arrives this week.
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Walter Winkel 2021-05-01
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A new startup is pouring millions into yet another attempt to bring internet stars to the big screen. But TikTok stars are not movies stars.
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Walter Winkel 2020-12-21
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The bill would cause more harms to sex workers than it would fix, critics argue.
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Walter Winkel 2020-09-02
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Parenting is tough in this oddball, adult sci-fi show from HBO.
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0
Walter Winkel 2021-07-09
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The photos, videos, and other "virulent screeds" forced those manning the hotline to beg for other duties, according to Michael Wolff's book.
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0
Walter Winkel 2021-04-16
img
After the storming of the Capitol on Jan. 6, what do consequences mean in this country-and who ends up facing them?
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0
Walter Winkel 2020-09-16
img
Have your 60fps-at-4K cake—and eat your ray-traced frosting, too.
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0
Walter Winkel 2020-08-12
img
From Huawei to Lenovo to Meizu, here's a breakdown of the players in the daunting landscape of Chinese smartphones.
collect
0
Walter Winkel 2021-07-27
img
Face-morphing adult content creator Coconut Kitty is ushering in the unsettling future of the medium, one where nothing is as it seems.
Walter Winkel 2021-07-12
img
New Zealand comedy Wellington Paranormal arrives this week.
Walter Winkel 2021-05-29
img
Welcome back to The TechCrunch Exchange, a weekly startups-and-markets newsletter for your weekend enjoyment.
Walter Winkel 2021-05-01
img
A new startup is pouring millions into yet another attempt to bring internet stars to the big screen. But TikTok stars are not movies stars.
Walter Winkel 2021-03-26
img

Women are much more likely than men to suffer from long Covid – where a host of debilitating symptoms last beyond four weeks, sometimes for more than a year. But the reason why this is the case hasn’t been made clear. 

Data from the Office for National Statistics (ONS) has repeatedly shown women tend to fare less well than men. And now, two new studies have shed more light on the gender disparities between those blighted by long-term symptoms of the virus and those who recover fairly quickly.

The first looked at the long-term effects of Covid-19 after hospital admission – 327 patients were discharged and followed up on to see how they recovered. Women under 50 had higher odds of worse long-term health outcomes when compared to men and older study participants.

Dr Janet Scott, lead author of the pre-print study, from the University of Glasgow-MRC Centre for Virus Research, said the finding could have “profound implications” for pandemic policy decision, as well as vaccination strategy.

Females under the age of 50 were five times less likely to report feeling fully recovered. They were twice as likely to report worse fatigue, seven times more likely to be breathless and more likely to have worsening difficulties or new disabilities than men of the same age.

A separate pre-print study looking at the impact of coronavirus on physical and mental health in adults discharged from hospital after having Covid-19 also found women were more impacted.

Patients were assessed between two and seven months later to see how they’d recovered. Factors associated with failure to recover included: being female, middle-aged, white ethnicity, having two or more underlying health issues, and having more severe acute illness from Covid.

Gender differences have been apparent since the start of the pandemic, when men were found to have more severe outcomes from Covid-19. They’re more likely to be hospitalised by the virus and end up in intensive care, and also twice as likely to die from the virus as women.

“We’ve appreciated throughout that there are gender differences in immunity to this virus,” Professor Daniel Altmann, of the Department of Immunology and Inflammation at Imperial College London, tells HuffPost UK. 

“In our data, women tend to have higher levels of antibody, while men tend to have higher levels of T-cell mediated immunity. As is now well appreciated, men tend to fare worse during severe, acute infection. That leaves the question of why women should be more susceptible to long Covid.”

The answer might lie in differences in how our immune systems work – or that’s what scientists hypothesise, anyway. Research is needed to look into this.

Dr Louise Newson, a GP and menopause specialist, previously said during a webinar that women have “a stronger response to infections, but especially to viruses, compared to men”. This is because women have different immune systems. She added that “frustratingly, so much research on immunity and in general is done in men and not in women”.

In a 2016 review on the differences in immune responses between males and females, professor Sabra Klein, of The Johns Hopkins Bloomberg School of Public Health, and professor Katie Flanagan, of Monash University, said females’ strong immune responses result in faster clearance of pathogens and greater vaccine efficacy compared to males. But it also contributes to females’ increased susceptibility to inflammatory and autoimmune diseases.

The sex hormone oestrogen could also play a role. A study by King’s College London (KCL) found post-menopausal women with lower levels of oestrogen appeared to be at higher risk of developing serious complications of Covid. 

The hormone, which declines in women as they age, interacts with the immune system in various ways, including influencing how many immune cells are produced and how they respond to infection.

Prof Altmann and others are looking at underpinning immune mechanisms that might explain the differences in how people recover from the virus – including the role of sex hormones. He points out women are more impacted by autoimmune diseases such as lupus and multiple sclerosis, which was “always taken to indicate interaction between sex hormones and the immune system”.

The interaction between sex hormones and the immune system now needs to feed into our thinking about long Covid, adds Prof Altmann. 

Walter Winkel 2020-12-21
img
The bill would cause more harms to sex workers than it would fix, critics argue.
Walter Winkel 2020-09-10
img

"Vulnerability disclosures do take very weird turns from time to time"

The post TERF Wars, “Random Twitter People” and Responsible Disclosure appeared first on Computer Business Review.

Walter Winkel 2020-09-02
img
Parenting is tough in this oddball, adult sci-fi show from HBO.
Walter Winkel 2021-07-18
img
The secret to getting cheap razors? Buy them online and have them delivered on a schedule.
Walter Winkel 2021-07-09
img
The photos, videos, and other "virulent screeds" forced those manning the hotline to beg for other duties, according to Michael Wolff's book.
Walter Winkel 2021-05-13
img

Reddit is building an in-house creative strategy agency, KarmaLab, in a broader bid in recent years to grow its ads business.

The post ‘Bridge the gap between paid and organic’: Why Reddit is building an in-house agency to work with brands appeared first on Digiday.

Walter Winkel 2021-04-16
img
After the storming of the Capitol on Jan. 6, what do consequences mean in this country-and who ends up facing them?
Walter Winkel 2021-02-25
img
A State Department spokesperson told Vice that the US complained to China after learning some diplomatic staff had been made to do anal swab tests.
Walter Winkel 2020-09-16
img
Have your 60fps-at-4K cake—and eat your ray-traced frosting, too.
Walter Winkel 2020-09-03
img
Genre-bending series like I May Destroy You and Lovecraft Country may be rooted in pain, but they’re also thrillingly hopeful.
Walter Winkel 2020-08-12
img
From Huawei to Lenovo to Meizu, here's a breakdown of the players in the daunting landscape of Chinese smartphones.