Maharshi Atreya Health Centre - Well known Ayurvedic Health Centre in India

Rising optometric clinical practice is expected to provide an impetus to the growth of the global uveitis treatment market. Growing prevalence of uveitis with the projects on development of biological drugs is expected to fuel the demand for uveitis treatment. In addition, surging prevalence of TB associated intermediate uveitis is further expected to boost the growth of the global uveitis treatment market in the future. Major players in the market are focusing on expanding their product portfolios, enhancing the demand for uveitis treatment.

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Global Uveitis Treatment Market Expected to Witness a Healthy Growth
Research Report Insights (RRI), in its research report, has provided a detailed analysis on the global uveitis treatment market for the forecast period of 2016 to 2024. RRI estimates that the market will grow at a healthy CAGR of 6.5% during the forecast period. Robust emergence of the immunosuppressive therapies for treating uveitis is expected to create new opportunities for leading market players in the future. Surge in autoimmune disorders is expected to primarily drive the demand for uveitis treatment across the globe. Generic drugs have been witnessing a rise in demand, generating opportunities for new as well as established pharma players. Huge investments have been made by several organisations in research and development activities for eye disorders. This is expected to fuel the market growth in the near future.

FDA Approved Adalimumab is Capable of Treating Uveitis
There is no doubt 2016 will be remembered as an innovative year for eye care in pharmaceuticals, and the patients, without doubt, will be the recipients of benefits of these innovations. The approval of adalimumab for treatment of uveitis has led eye care providers to expand the therapeutic armamentarium for managing this destructive inflammatory disease. Food and Drug Administration of the U.S. has approved the utilization of adalimumab in June 2016 for treatment of intermediate, non-infectious, and posterior uveitis, and panuveitis. The decision of regulatory approval was based on results of the two three-phase studies. Both of these studies were placebo controlled and double masked, both enrolling adult patients suffering from active & controlled intermediate non-infectious and posterior uveitis, and panuveitis. Investigators found that the treatment failures in patients treated with adalimumab were significantly lower as compared to those receiving placebo.

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Ribonucleic Acid Interface Therapeutic Agent Developed for Treating Uveitis
A new treatment is expected to eliminate the complications associated with utilisation of steroid in treatment of uveitis. Researchers from Hokkaido University have utilized a new therapeutic agent- ribonucleic acid interface (RNAi) for prevention of ocular inflammation in mice. This development is expected to offer an alternative for treating inflammatory eye diseases with corticosteroids. Long-term usage of these drugs may result into complications such as hypertension, glaucoma, osteoporosis, and cataracts.

The development of new RNAi therapeutic agent safely blocked the ocular inflammation in mice. This is expected to be a new treatment for diabetic retinopathy and uveitis in humans. Researchers were able to depict activation of the receptor-associated prorenin system (RAPS), involving in pathogenesis of uveitis. Scientists came up with the development of an interference agent, targeting this system, and injected it into the mice’s eyes. Significant improvement in the mouse models of chronic diabetic inflammation and acute uveitis was shown by the agent, without any side effects apparently.

The report profiles key market players and highlights their recent activities supporting market growth.
Allergan, Inc., Novartis AG (ALCON), Valeant Pharmaceuticals International, Inc., AbbVie Inc., Eyegate Pharmaceuticals, Inc., Alimera Sciences Inc., and pSivida Corp. are some of the key players in the global uveitis treatment market.

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The Federal Food, Drug, and Cosmetic Act (FD) has enacted a law under Section 745A(a) that the regulatory submissions including investigational new drug applications (INDs), new drug applications (NDAs), abbreviated new drug applications (ANDAs) and biologics license applications (BLAs) should be submitted in electronic format to Food and Drug Administration (FDA).

The ESG does not have access to open the documents, and it only receives, acknowledges receipt and directs the submission to the appropriate FDA center providing notification of delivery to the center.

At the first time, a draft protocol is presented to FDA for review, and it is called an original document.

All the amended submissions are based on the previous submissions except the original one.

FDA provides two options for review, i.e, Current View and Cumulative View: Current View shows only the current version of the document and does not show documents that have been deleted or replaced, and the Cumulative View shows the full lifecycle including all the versions that existed before the current version.

The validation and review of the study data are done at regular intervals throughout the submission process.

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Traditional generic drugs, on the other hand, are versions of a drug that are equivalent to a brand-name drug in active ingredients and effects but may have slight variations, such as in inactive ingredients like fillers and flavors.

EpiPen maker Mylan reveals generic—it’s only triple the price

High-profile examples of authorized generics include Mylan’s cheaper form of its EpiPen, a life-saving epinephrine autoinjector that curbs deadly allergic reactions.

But it’s still a staggering hike from EpiPen’s original cost of around $50 per injector in 2007.

That year, Mylan bought the rights to EpiPen and then raised the price more than 400% in the years that followed.

Moreover, because brand-name drugs’ list prices are often subject to rebates and discounts by middlemen, the authorized generics’ lower prices sometimes have no impact on how much drug companies net for their drugs.