Functional Testing Vs Non-Functional Testing

Let’s take a look at the non-functional excipients that are commonly used in solid oral preparations.DisintegrantThe disintegration of solid oral tablets is very important, because for most solid oral tablets, only after disintegration can the subsequent drug be dissolved and absorbed in the body.

In the prescription, the use of natural polymers as disintegrants may cause the viscosity of the surrounding medium to increase due to the partially soluble nature of the polymer, thereby hindering disintegration and dissolution.

This problem can be solved by two methods: polymer crosslinking (to reduce the viscosity of the disintegrant) and introducing carboxyl functional groups into the polymer (to increase hydrophilicity).The mechanism of action of disintegrants includes swelling, gas production, capillary action, and wetting and heat production.

The effect of moisturizing and heat generation is that some disintegrants will break the chemical bonds when they meet with water, thereby releasing heat and expanding the air remaining in the tablet to promote disintegration.pH regulatorThe pH of the microenvironment can affect the solubility, dissolution, degradation rate and stability of solid preparations.

For weakly acidic drugs, calcium phosphate, magnesium hydroxide, magnesium oxide, meglumine and sodium carbonate can be used as alkalizing agents.Fillers and adhesivesThe role of filler is to provide a certain volume for the formulation, so that the formulation can be processed into shape.

Fillers can be divided into water-soluble fillers and water-insoluble fillers.

Functional vs Non-functional Requirements: List & ExamplesPrecise functional and non-functional requirements are essential to reduce development costs because, when the requirements are clear, the team can develop the project much faster.

The difference between functional and non-functional requirements is as follows: Functional requirements are easy to define because the business idea drives them.

They include all the features of your future project and ways users engage with it.Experience drives Non-functional requirements.

In order, to identify them, you need to analyze the product's performance and make it convenient and useful.

Such requirements may appear when the product is being used on a regular basis.In this way, while functional requirements describe what the system does, non-functional requirements describe how the system works.

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