Roots Analysis has done a detailed study on “HPAPI and Cytotoxic Drugs Manufacturing (3rd Edition) 2020- 2030”, covering key aspects of the industry’s evolution and identifying potential future growth opportunities.
To order this 300+ page report, which features 75+ figures and 150+ tables, please visit this link
Key Market Insights
- Close to 120 companies across the globe claim to possess the required expertise and infrastructure to offer contract manufacturing services for HPAPIs and cytotoxic drugs
- The market is fragmented, featuring the presence of both established players and new entrants based in different geographies that claim to be capable of manufacturing highly potent products, at varying scales of operation
- In order to acquire competencies across the supply chain and cater to evolving needs of sponsors, companies offering services across different scales of operation have established presence in various geographical regions
- In recent years, a steady increase in partnership activity has been observed in this domain; a variety of deals have been inked related to highly potent drug products
- In order to enhance the core competencies in this domain, CMOs are actively investing in upgrading existing infrastructure and expanding their respective manufacturing capacities
- Most of the installed, global HPAPI and cytotoxic drug manufacturing capacity belongs to established CMOs, accounting for close to 75% of the available capacity across various geographies
- Case-in-point: ADCs represent a significant growth opportunity; over 30 CMOs currently extend their services to manufacture one or multiple components of an ADC molecule
- We expect highly potent drug developers to continue to outsource their manufacturing operations in the mid to long term, causing service-based revenues to grow at an annualized rate of more than 10%
- In the long-term, the projected opportunity for the contract manufacturing of HPAPIs and cytotoxic drugs is likely to be well distributed across various dosage forms, nature of molecules and sizes of contract service providers
For more information, please visit https://www.rootsanalysis.com/reports/view_document/hpapi-and-cytotoxic-drugs-manufacturing/299.html
Table of Contents
- PREFACE
1.1. Scope of the Report
1.2. Research Methodology
1.3. Chapter Outlines
2. EXECUTIVE SUMMARY
3. INTRODUCTION
3.1. Chapter Overview
3.2. Overview of Highly Potent Active Pharmaceutical Ingredients (HPAPIs)
3.2.1. Classification based on Potency of Pharmacological Ingredients
3.2.2. Types of HPAPIs
3.2.3. Challenges Associated with Handling HPAPIs
3.2.4. Considerations for Handling HPAPIs
3.2.5. Contract Manufacturing of HPAPIs and Cytotoxic Drugs
3.2.5.1. Selection of a Suitable CMO Partner for HPAPI Manufacturing
3.2.6. Regulatory Considerations for HPAPI Manufacturing
3.2.7. Concluding Remarks - MARKET LANDSCAPE
4.1. Chapter Overview
4.2. HPAPI and Cytotoxic Drugs Contract Manufacturers: Overall Market Landscape
4.2.1. Analysis by Year of Establishment
4.2.2. Analysis by Company Size
4.2.3. Analysis by Scale of Operation
4.2.4. Analysis by Type of Service(s) Offered
4.2.5. Analysis by Type of Product
4.2.6. Analysis by Type of Pharmacological Molecule
4.2.7. Analysis by Location of Headquarters
4.2.8. Analysis by Location of Manufacturing Facilities
4.2.9. Analysis by Facility Size
4.2.10. Analysis by Type of Highly Potent Finished Dosage Forms (FDFs)
4.2.11. Analysis by Type of Primary Packaging
- COMPANY COMPETITIVE ANALYSIS
5.1. Chapter Overview
5.2. Methodology
5.3. Assumptions and Key Parameters
5.4. Company Competitiveness Analysis: HPAPI and Cytotoxic Drugs Contract Manufacturers based in North America
5.5. Company Competitiveness Analysis: HPAPI and Cytotoxic Drugs Contract Manufacturers based in Europe
5.6. Company Competitiveness Analysis: HPAPI and Cytotoxic Drugs Contract Manufacturers based in Asia Pacific and Rest of the World
- HPAPI AND CYTOTOXIC DRUGS CONTRACT MANUFACTURERS BASED IN NORTH AMERICA: COMPANY PROFILES
6.1. Chapter Overview
6.2. AbbVie Contract Manufacturing
6.2.1. Company Overview
6.2.1.1. HPAPI and Cytotoxic Drugs Manufacturing Service Offerings
6.2.1.2. Manufacturing Facilities
6.2.1.3. Recent Developments
6.2.1.4. Future Outlook
6.3. Catalent
6.3.1. Company Overview
6.3.1.1. HPAPI and Cytotoxic Drugs Manufacturing Service Offerings
6.3.1.2. Manufacturing Facilities
6.3.1.3. Recent Developments
6.3.1.4. Future Outlook
6.4. Pfizer CentreOne
6.4.1. Company Overview
6.4.1.1. HPAPI and Cytotoxic Drugs Manufacturing Service Offerings
6.4.1.2. Manufacturing Facilities
6.4.1.3. Recent Developments
6.4.1.4. Future Outlook
6.5. Piramal Pharma Solutions
6.5.1. Company Overview
6.5.1.1. HPAPI and Cytotoxic Drugs Manufacturing Service Offerings
6.5.1.2. Manufacturing Facilities
6.5.1.3. Recent Developments
6.5.1.4. Future Outlook
6.6. SAFC (a business division of Sigma-Aldrich)
6.6.1. Company Overview
6.6.1.1. HPAPI and Cytotoxic Drugs Manufacturing Service Offerings
6.6.1.2. Manufacturing Facilities
6.6.1.3. Recent Developments
6.6.1.4. Future Outlook
- HPAPI AND CYTOTOXIC DRUGS CONTRACT MANUFACTURERS BASED IN EUROPE: COMPANY PROFILES
7.1. Chapter Overview
7.2. Carbogen Amics
7.2.1. Company Overview
7.2.1.1. HPAPI and Cytotoxic Drugs Manufacturing Service Offerings
7.2.1.2. Manufacturing Facilities
7.2.1.3. Recent Developments
7.2.1.4. Future Outlook
7.3. Evonik
7.3.1. Company Overview
7.3.1.1. HPAPI and Cytotoxic Drugs Manufacturing Service Offerings
7.3.1.2. Manufacturing Facilities
7.3.1.3. Recent Developments
7.3.1.4. Future Outlook
7.4. Lonza
7.4.1. Company Overview
7.4.1.1. HPAPI and Cytotoxic Drugs Manufacturing Service Offerings
7.4.1.2. Manufacturing Facilities
7.4.1.3. Recent Developments
7.4.1.4. Future Outlook
7.5. Siegfried
7.5.1. Company Overview
7.5.1.1. HPAPI and Cytotoxic Drugs Manufacturing Service Offerings
7.5.1.2. Manufacturing Facilities
7.5.1.3. Recent Developments
7.5.1.4. Future Outlook
7.6. Teva API
7.6.1. Company Overview
7.6.1.1. HPAPI and Cytotoxic Drugs Manufacturing Service Offerings
7.6.1.2. Manufacturing Facilities
7.6.1.3. Recent Developments
7.6.1.4. Future Outlook
- HPAPI AND CYTOTOXIC DRUGS CONTRACT MANUFACTURERS BASED IN ASIA PACIFIC: COMPANY PROFILES
8.1. Chapter Overview
8.2. Formosa Laboratories
8.2.1. Company Overview
8.2.1.1. HPAPI and Cytotoxic Drugs Manufacturing Service Offerings
8.2.1.2. Manufacturing Facilities
8.2.1.3. Recent Developments
8.2.1.4. Future Outlook
8.3. Intas Pharmaceuticals
8.3.1. Company Overview
8.3.1.1. HPAPI and Cytotoxic Drugs Manufacturing Service Offerings
8.3.1.2. Manufacturing Facilities
8.3.1.3. Future Outlook
8.4. MabPlex
8.4.1. Company Overview
8.4.1.1. HPAPI and Cytotoxic Drugs Manufacturing Service Offerings
8.4.1.2. Manufacturing Facilities
8.4.1.3. Future Outlook
8.5. ScinoPharm
8.5.1. Company Overview
8.5.1.1. HPAPIs and Cytotoxic Drugs Manufacturing Service Offerings
8.5.1.2. Manufacturing Facilities
8.5.1.3. Future Outlook
8.6. STA Pharmaceutical (a WuXi AppTec company)
8.6.1. Company Overview
8.6.1.1. HPAPI and Cytotoxic Drugs Manufacturing Service Offerings
8.6.1.2. Manufacturing Facilities
8.6.1.3. Recent Developments
8.6.1.4. Future Outlook
- PARTNERSHIPS AND COLLABORATIONS
9.1. Chapter Overview
9.2. Partnership Models
9.3. HPAPI and Cytotoxic Drugs Contract Manufacturers: List of Partnerships and Collaborations
9.3.1. Analysis by Year of Partnership
9.3.2. Analysis by Type of Partnership
9.3.3. Analysis by Type of Product
9.3.4. Analysis by Scale of Operation
9.3.5. Analysis by Company Size
9.3.6. Analysis of Acquisitions by Amount Invested
9.3.7. Most Active Players: Analysis by Number of Partnerships
9.3.8. Geographical Analysis
9.3.8.1. Continent-wise Distribution
9.3.8.2. Country-wise Distribution
- RECENT EXPANSIONS
10.1. Chapter Overview
10.2. HPAPI and Cytotoxic Drugs Contract Manufacturers: Recent Expansions
10.2.1. Analysis by Year of Expansion
10.2.2. Analysis by Type of Expansion
10.2.3. Analysis by Scale of Operation and Type of Expansion
10.2.4. Analysis by Type of Product and Type of Expansion
10.2.5. Analysis by Expanded Facility Area
10.2.6. Analysis by Amount Invested
10.2.7. Analysis by Company Headquarters and Company Size
10.2.8. Analysis by Location of Facility and Type of Expansion
10.2.9. Most Active Players: Analysis by Number of Expansions
10.2.10. Geographical Analysis
10.2.10.1. Continent-wise Distribution
10.2.10.2. Country-wise Distribution
- CAPACITY ANALYSIS
11.1. Chapter Overview
11.2. Key Assumptions and Methodology
11.3. HPAPI and Cytotoxic Drugs Contract Manufacturers: Global, Installed Capacity
11.3.1. Analysis by Company Size
11.3.2. Analysis by Scale of Operation
11.3.3. Analysis by Location of Manufacturing Facility
11.4. Concluding Remarks
- MAKE VERSUS BUY DECISION MAKING FRAMEWORK
12.1. Chapter Overview
12.2. HPAPI and Cytotoxic Drugs Contract Manufacturing: Make versus Buy Decision Making
- MARKET SIZING AND OPPORTUNITY ANALYSIS
13.1. Chapter Overview
13.2. Forecast Methodology and Key Assumptions
13.3. Overall HPAPI and Cytotoxic Drugs Contract Manufacturing Market, 2020-2030
13.4. HPAPI and Cytotoxic Drugs Contract Manufacturing Market, 2020-2030: Distribution by Type of Product
13.5. HPAPI and Cytotoxic Drugs Contract Manufacturing Market, 2020-2030: Distribution by Company Size
13.6. HPAPI and Cytotoxic Drugs Contract Manufacturing Market, 2020-2030: Distribution by Scale of Operation
13.7. HPAPI and Cytotoxic Drugs Contract Manufacturing Market, 2020-2030: Distribution by Type of Pharmacological Molecule
13.8. HPAPI and Cytotoxic Drugs Contract Manufacturing Market, 2020-2030: Distribution by Type of Highly Potent Finished Dosage Forms
13.9. HPAPI and Cytotoxic Drugs Contract Manufacturing Market, 2020-2030: Distribution across Key Geographical Regions
13.9.1. HPAPI and Cytotoxic Drugs Contract Manufacturing Market in North America, 2020-2030
13.9.1.1. HPAPI and Cytotoxic Drugs Contract Manufacturing Market in the US, 2020-2030
13.9.1.2. HPAPI and Cytotoxic Drugs Contract Manufacturing Market in Canada, 2020-2030
13.9.1.3. HPAPI and Cytotoxic Drugs Contract Manufacturing Market in Mexico, 2020-2030
13.9.2. HPAPI and Cytotoxic Drugs Contract Manufacturing Market in Europe, 2020-2030
13.9.2.1. HPAPI and Cytotoxic Drugs Contract Manufacturing Market in the UK, 2020-2030
13.9.2.2. HPAPI and Cytotoxic Drugs Contract Manufacturing Market in Italy, 2020-2030
13.9.2.3. HPAPI and Cytotoxic Drugs Contract Manufacturing Market in Germany, 2020-2030
13.9.2.4. HPAPI and Cytotoxic Drugs Contract Manufacturing Market in France, 2020-2030
13.8.2.5. HPAPI and Cytotoxic Drugs Contract Manufacturing Market in Spain, 2020-2030
13.9.2.6. HPAPI and Cytotoxic Drugs Contract Manufacturing Market in Rest of Europe, 2020-2030
13.9.3. HPAPI and Cytotoxic Drugs Contract Manufacturing Market in Asia Pacific, 2020-2030 (USD Billion)
13.9.3.1. HPAPI and Cytotoxic Drugs Contract Manufacturing Market in China, 2020-2030
13.9.3.2. HPAPI and Cytotoxic Drugs Contract Manufacturing Market in India, 2020-2030
13.9.3.3. HPAPI and Cytotoxic Drugs Contract Manufacturing Market in Rest of Asia Pacific, 2020-2030
13.9.4. HPAPI and Cytotoxic Drugs Contract Manufacturing Market in the Rest of the World, 2020-2030
- SWOT ANALYSIS
14.1. Chapter Overview
14.2. Strengths
14.3. Weaknesses
14.4. Opportunities
14.5. Threats
14.6. Concluding Remarks
- CASE-IN-POINT: CONTRACT MANUFACTURING OF ANTIBODY DRUG CONJUGATES
15.1. Chapter Overview
15.2. Key Components of ADCs
15.2.1. Antibody
15.2.2. Cytotoxin
15.2.3. Linker
15.3. Overview of ADC Manufacturing
15.3.1. Key Process Steps
15.3.2. Challenges Associated with ADC Manufacturing
15.3.3. Growing Trend of Outsourcing in ADC Manufacturing
15.4. Challenges Associated with Supply Chain and Method Transfer
15.5. Growing Demand for One-Stop-Shops and Integrated Service Providers
15.6. Key Considerations for Selecting a CMO Partner
15.7. ADC Contract Manufacturers: Overall Market Landscape
15.7.1. Analysis by Location of Headquarters
15.7.2. Analysis by Year of Establishment
15.7.3. Analysis by Company Size
15.7.4. Analysis by Service(s) Offered
15.7.5. Analysis by Location of Headquarters
15.7.5. Analysis by Location of Manufacturing Facility
15.7.6. Analysis by Scale of Operation
- CONCLUDING REMARKS
- EXECUTIVE INSIGHTS
17.1. Chapter Overview
17.2. BSP Pharmaceuticals
17.2.1. Company Snapshot
17.2.2. Interview Transcript: Antonella Mancuso and Maria Elena Guadagno, Vice President and Chief Operating Officer and Business Director
17.3. Catalent
17.3.1. Company Snapshot
17.3.2. Interview Transcript: Stacy McDonald and Jennifer L. Mitcham, Group Product Manager and Director-Business Development
17.4. CordenPharma
17.4.1. Company Snapshot
17.4.2. Interview Transcript: Roberto Margarita, Business Development Director
17.5. Helsinn
17.5.1. Company Snapshot
17.5.2. Interview Transcript: Allison Vavala, Senior Manager, Business Development
17.6. Idifarma
17.6.1. Company Snapshot
17.6.2. Interview Transcript: Javier E. Aznárez Araiz, Business Development
17.7. Piramal Healthcare
17.7.1. Company Snapshot
17.7.2. Interview Transcript: Dr. Mark Wright, Site Head, Grangemouth
17.8 ProJect Pharmaceutics
17.8.1. Company Snapshot
17.8.2. Interview Transcript: Klaus Hellerbrand, Managing Director
17.9. Alphora Research
17.9.1. Company Snapshot
17.9.2. Interview Transcript: Kevin Rosenthal, Business Head, Formulations and Finished Products
- APPENDIX 1: TABULATED DATA
- APPENDIX 2: LIST OF COMPANIES AND ORGANIZATIONS
Contact Details
Gaurav Chaudhary
+1 (415) 800 3415
Outsourcing has become a popular trend among biopharmaceutical developers, allowing them to leverage the expertise / larger production capacities of CMOs / CDMOs and achieve significant cost and time related advantages Roots Analysis is pleased to announce the publication of its recent study, titled, “Biopharma Contract Manufacturing Market (3rd Edition), 2019-2030.” The report features an extensive study on the contract service providers within the biopharmaceutical industry.
The study features in-depth analysis, highlighting the capabilities of a diverse set of biopharmaceutical CMOs and CDMOs.
Amongst other elements, the report includes:A detailed review of the overall landscape of the biopharmaceutical contract manufacturing market, featuring a comprehensive list of active CMOs and detailed analysis of the manufacturing service providers based on a number of parameters.Elaborate profiles of key players that have a diverse range of capabilities for the development, manufacturing, and packaging of biologics.A detailed discussion on the key enablers in this domain, including certain niche product classes, which are likely to have a significant impact on the growth of the contract services market.A case study on the growing global biosimilars market, highlighting the opportunities for biopharmaceutical CMOs and CDMOs.A case study comparing the key characteristics of large molecule and small molecule drugs, along with details on the various steps involved in their respective manufacturing processes.A discussion on challenges related to in-house manufacturing, featuring a brief overview of the various parameters that a drug / therapy developer may need to take into consideration while deciding whether to manufacture its products in-house or outsource.An analysis of the recent collaborations (signed since 2013) focused on the contract manufacturing of biologics.A detailed analysis of the various mergers and acquisitions that have taken place in this domain, highlighting the trend in the number of companies acquired between 2013-2018, along with the geographical distribution of this activity.An in-depth analysis of more than 490 grants that have been awarded to research institutes engaged in next generation immune checkpoint therapy-related projects.An analysis on the recent trends within biopharmaceutical contract manufacturing industry, highlighting various facility and capability expansions.A detailed capacity analysis, taking into consideration the individual development and manufacturing capacities of various stakeholders.A detailed capacity analysis, taking into consideration the individual development and manufacturing capacities of various stakeholders.A discussion on affiliated trends, key drivers, and challenges, under a comprehensive SWOT framework.A survey analysis featuring inputs solicited from various experts who are directly / indirectly involved in providing CMO services to medical device developers.A detailed market forecast, featuring analysis of the current and projected future opportunity across key market segments (listed below)Commonly Outsourced Business OperationsActive Pharmaceutical Ingredients (API)Finished Dosage Formulations (FDF)Types of Expression SystemMammalianMicrobialOthersCompany SizeSmallMid-SizedLarge and Very LargeScale of OperationPreclinicalClinicalCommercialKey Geographical Region North AmericaEuropeAsia-PacificRest of the World The report also features detailed transcripts of discussions held with the following experts:Astrid Brammer, Senior Manager Business Development, Richter-Helm Mathias Schmidt (Chief Executive Officer, ArmaGen)Birgit Schwab, Senior Manager Strategic Marketing, Rentschler BiotechnologieChristian Bailly, Director of CDMO, Pierre FabreClaire Otjes, Assistant Marketing Manager, Batavia BiosciencesDavid C Cunningham, Director Corporate Development, Goodwin BiotechnologyDietmar Katinger, Chief Executive Officer, Polymun ScientificDenis Angioletti, Chief Commercial Officer, Cerbios-PharmaJeffrey Hung, Chief Commercial Officer, Vigene BiosciencesKevin Daley, Director Pharmaceuticals, NovasepMark Wright, Site Head, Grangemouth, Piramal HealthcareNicolas Grandchamp, R Leader, GEG TechRaquel Fortunato, Chief Executive Officer, GenIbet BiopharmaceuticalsSebastian Schuck, Head of Business Development, Wacker BiotechStephen Taylor, Senior Vice President Commercial, FUJIFILM Diosynth BiotechnologiesTatjana Buchholz, Marketing Manager, PlasmidFactory and Marco Schmeer, Project Manager, PlasmidFactoryTim Oldham, Chief Executive Officer, Cell Therapies To request for sample report - https://www.rootsanalysis.com/reports/view_document/biopharmaceutical-contract-manufacturing-market/250.html Key companies covered in the report3P BiopharmaceuticalsAbzenaAlbany Molecular ResearchBioVectraBioXcellence (Boehringer Ingelheim)CelonicCharles River LaboratoriesChemPartnerCobra BiologicsCordenPharmaCytovance BiologicsGE HealthcareGoodwin BiotechnologyGrand River Aseptic ManufacturingIDT BiologikaKBI BioPharmaKemwell BiopharmaLFB BiomanufacturingMeridian Life SciencePatheonPfizer CentreOnePX'TherapeuticsSamsung BioLogicsSanofi, CEPiAThermo Fisher ScientificVetter Pharma International For more information please click on the following link:Biopharma Contract Manufacturing Market (3rd Edition), 2019-2030 Other Recent OfferingsCell Therapy Manufacturing Market (3rd Edition), 2019-2030Antibody Contract Manufacturing Market, 2020-2030China Biopharmaceutical Contract Manufacturing Market, 2020-2030Peptide Therapeutics: Contract API Manufacturing Market, 2020-2030 About Roots AnalysisRoots Analysis is one of the fastest growing market research companies, sharing fresh and independent perspectives in the bio-pharmaceutical industry.
The in-depth research, analysis and insights are driven by an experienced leadership team which has gained many years of significant experience in this sector.
If you’d like help with your growing business needs, get in touch at [email protected] Contact InformationRoots Analysis Private LimitedGaurav Chaudhary+1 (415) 800 [email protected] - https://www.facebook.com/RootsAnalysis
The Biofertilizers Market Research Report 2019 gives an extensive evaluation of the industry to help the reader gain the upper hand in the competitive landscape by employing optimal tactics and understanding the essential market elements in the Biofertilizers sector.
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Acute Lymphocytic-Lymphoblastic Leukemia Therapeutics Market are the collection of drugs and therapeutic systems available in the market for its treatment.
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This rise in market value can be attributed to the growing levels of preference for adopting targeted therapy systems as well as increasing prevalence of bone marrow biopsies carried out.Acute lymphocytic/lymphoblastic leukemia (ALL) therapeutics are the collection of drugs and therapeutic systems available in the market for its treatment.
