
The initial dosage for patients who are not opioid-tolerant
is 10 mg OxyContin orally every 12 hours.
Using higher starting doses in patients who are not opioid-tolerant may
result in fatal respiratory depression.
Overdose
An oxycodone overdose is fatal, especially in a child or someone taking the medication without a prescription. The overdose can cause severe drowsiness, pinpoint pupils, slow breathing, or no breathing.
Your doctor may advise you to get naloxone, a medicine that helps reverse an opioid overdose. If you stop breathing or do not wake up, a caregiver can administer naloxone.