Gastroesophageal Reflux Disease is an unpleasant condition that occurs as a heartburn, swallowing difficulty, regurgitation and other physical complications. This condition occurs when our stomach acid continuously flows back into the tube connecting the mouth and stomach. GERD is a widely spread health condition that affects approximately one out of every five people in the western world. People with severe asthma symptoms are more likely to experience this disease. Asthma flare-ups can cause the esophageal sphincter to relax and let stomach contents flow back. Certain asthma medicines, both OTC and prescription, can worsen reflux symptoms. At the same time, acid reflux can worsen asthma symptoms by irritating the lungs and airways. This unnecessary irritation can trigger an allergic reaction and make your airways more sensitive to environmental conditions like cold air or smoke.
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The global Gastroesophageal Reflux Disease (GERD) therapeutics market size was valued at USD 5.66 billion in 2016 and by is estimated to be USD 4.34 billion by 2025, it is anticipated to observe a decrease in its revenue at a negative CAGR of -2.9%.
Expiration of patented blockbuster drugs, which are indicated for the management of disorders of acid reflux is major restraining factors for this market.
Rising number of companies being exposed to price scrutiny associated with shift in the focus of government on the promotion of consumer convenience will stimulate further reduction of drug prices.
Although market turnover is affected by the expiration of major patents and the demand of drugs used to reduce acid, due to the increasing prevalence of heartburn, is anticipated to increase in the upcoming years.
Hence, very limited acceptance of devices of GERD management contribute for the rising demand of drugs having acid neutralizing property, as the major therapy approach.
Nevertheless, the advent of devices which are minimally invasive to address anatomical defects are gaining popularity coupled with supportive evidence from clinical data for performing various procedures including trans oral fundoplication, which helps in preventing reflux of non-acid and acid contents.
