Imatinib is the brand name for the drug called Gleevec. It is used to treat some types of cancers (myeloid leukaemia, gastrointestinal stromal tumours, and others). Imatinib is a pill taken by mouth.
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Brand Name : Imatikast
Form : Tablets
Generic Name : Imatikast 100mg
Salt Name : Imatinib
Manufactured by : Aprazer
Strength : 100 mg
Packing : 3 x 10 tablets
SKU: imatinib-tablets-100-mg
Categories: Anti Cancer, Hematology-Oncology, Leukemia, Products
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Generic: ImatinibBrand: GleevecImatinib Mesylate is a medication used for the treatment of certain kinds of cancers such aschronic myeloid leukemiagastrointestinal stomach tumoursacute lymphoblastic leukemiamyelodysplastic / myeloproliferative diseasesImatinib / Gleevec is a chemotherapeutic medication which is used to slow down or stop tumour growth.Imatinib / Gleevec cost informationImatinib (Gleevec) is proven to be highly effective in treating chronic myeloid leukemia and gastrointestinal tumors.
However, the recommended daily dose of 400-600 mg requires taking several capsules of 100 mg dosage or a combination of 100 mg and 400 mg capsules.
Swallowing multiple capsules at the same time may have negative impact on treatment adherence.In response to this problem, imatinib 100 mg and 400 mg film-coated tablets were developed.
Additionally, a research test was conducted to study their effectiveness.Research OverviewA group of 33 candidates were on random assigned to 1 of the 6 treatment combination of imatinib capsules / tablets.The candidates were given either of the following:Four 100 mg capsules as a reference pointFour 100 mg scored tablets for testingOne 400 mg tablet for testingAfter 96 hours of taking the doses, blood sampling tests were performed.
This was followed by a 10 day period of washout before the next sequence can start.After receiving the 3rd dose, the candidates were observed for adverse events due to the medication.Results95% of the confidence intervals were within the pre-determined intervals.
1 moderate and 8 mild adverse events were reported that could have been related to the medication.However, these events were of no clinical significance as no clustering by type of the dosage form was observed.ConclusionThe 100 mg film coated tablets (scored) and the 400 mg tablets were deemed to be as safe and tolerated as the commercial 100 mg hard gelatin capsules.Imatinib Mesylate UsageImatinib (Gleevec) tablets are generally taken once or twice in a day with a meal and a glass of water (240 ml or 8 ounces) or as directed by a doctor.Do not crush, chew or break the tablet.If you are facing difficulty in swallowing the tablet.