Respiratory drug delivery is the process of administering drugs to the respiratory system (lungs, bronchi, and trachea) to treat various respiratory diseases such as asthma, chronic obstructive pulmonary disease (COPD), cystic fibrosis, and others. The respiratory drug delivery formulation is the process of developing a drug in a form that can be effectively delivered to the respiratory system.
Respiratory drug delivery formulations refer to the different ways in which drugs are delivered to the respiratory system. The main goal of respiratory drug delivery formulations is to deliver a precise and effective dose of medication to the targeted area in the respiratory system.
Some common respiratory drug delivery formulations include:
Inhalers: Inhalers are devices that deliver drugs in the form of a mist or spray. There are different types of inhalers including metered-dose inhalers (MDI), dry powder inhalers (DPI), and nebulizers.
DPI (Dry Powder Inhalers): DPI is a type of inhaler that delivers dry powder medication to the respiratory system. This type of inhaler is often preferred because it is easy to use and does not require coordination between inhaling and pressing a button.
MDI (Metered-Dose Inhalers): MDI is a type of inhaler that delivers a metered dose of medication in the form of a spray. This type of inhaler is often preferred because it is convenient and can be carried around easily.
Nebulizers: Nebulizers are devices that deliver medication in the form of a mist. They are commonly used in hospitals and at home for the treatment of severe respiratory diseases such as cystic fibrosis.
Intravenous (IV) injections: IV injections are used to deliver drugs directly into the bloodstream. This type of delivery is often used in severe respiratory cases or when the patient is unable to use an inhaler.
Intramuscular (IM) injections: IM injections are used to deliver drugs directly into the muscles. This type of delivery is often used when the patient is unable to use an inhaler or when the drug needs to be delivered quickly.
The choice of respiratory drug delivery formulation depends on various factors such as the type of disease, the age of the patient, and the severity of the disease. A healthcare professional can help determine the best respiratory drug delivery formulation for a particular patient.
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Increasing preference of pulmonary route of drug delivery, increasing technological developments in the form of smart/digital inhalers and rising incidences of respiratory diseases such as COPD, asthma, and cystic fibrosis.Global respiratory drug delivery market is projected to reach USD 52.37 Billion by 2021 from USD 36.10 Billion in 2016, at a CAGR of 6.5%.
Pulmonary/ Respiratory Drug Delivery Market by Formulation (Type (Solution, Suspension, Dry powder), Device Type (Metered dose, Dry Powder, Nebulizer)), Canister (Plain, Coated), End User (Hospitals, Homecare), Applications (COPD).Emerging markets such as India, China, & Japan and growth in online marketing channels are expected to offer lucrative growth opportunities for market players in the coming years.
On the other hand, factors such as regulatory issues and pricing pressures are the major factors restraining Respiratory Drug Delivery market growth.The pulmonary drug delivery market is segmented based on formulations, canister type, applications, end users, and regions.
On the basis of end user, the market is segmented into hospitals & clinics and homecare settings.
The hospitals & clinics segment dominated the market in 2016, this is attributed to the increasing incidence of diseases such as pneumonia and acute exacerbation of COPD (AECOPD) is driving the number of hospitalizations each year.Based on canister type, the Respiratory Drug Delivery Market is segmented into plain and coated canister.
The coated canister segment is expected to be the fastest growing market in canister type segments in the respiratory Drug Delivery Market during the forecast period.
Recognized as a CRO for pharmaceutical formulation, CD Formulation recently announces to have optimized its stability analysis service, providing solid-state stability analysis, solution-state stability analysis, APIs-excipients compatibility analysis for researchers devoted to drug formulation research.
Current Good Manufacturing Practice for Finished Pharmaceuticals (CGMPs) has already established requirements on the expiration date and stability testing of drug products to assure the appropriateness of that date.“Stability analysis is of vital importance because it can help prove and ensure the product quality, safety and efficacy of drug products when exposed to environmental factors such as temperature, humidity and light.
Any drugs need stability testing documents before they are accepted and approved by regulatory agencies.
At CD Formulation, we conduct stability studies in a planned way following the guidelines issued by ICH, WHO and or other agencies,” says the Marketing Chief of CD Formulation.
“Our methods for stability analysis include but are not limited to Thermogravimetric Analysis (TG), Raman Spectroscopy, FT-IR Spectroscopy, Differential Scanning Calorimetry (DSC), High-performance Liquid Chromatography (HPLC), and X-ray Diffraction.”After elucidating how the chemical, physical and microbiological changes will influence the effectiveness, stability and safety of the final drug product and make recommendations on how to best store drugs, scientists at CD Formulation will also help clients to make a decision for operational and procedural conditions that can ensure the physical and chemical stability and pharmacological activity of the product to minimize potential formulation and stability issues.Besides stability analysis, CD Formulation also provides other pre-formulation services like crystallinity determination, amorphous content determination, hygroscopicity evaluation, particle size analysis, moisture content determination, solubility analysis, LogP/LogD/pKa analysis, stability analysis, and API-excipient compatibility for pharmaceutical companies.
Visit: https://www.formulationbio.com/preformulation.html to learn more information.About CD FormulationThe increasing demand for greater flexibility and efficiency in drug development has made innovative drug formulations more valuable.
