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DNA Profiling Tests in India - Uses & Its Applications

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DNA Forensics Laboratory

DNA fingerprinting is a technique used by forensic scientists to help identify people or samples by their respective DNA profiles. Over 99.9% of the genome is the same throughout the human population. The remaining 0.1% of human DNA shows variations between people. These variable DNA sequences, known as polymorphic markers, can be used to both distinguish and correlate people. DNA fingerprinting is also called DNA profiling or forensic genetics. 





What are the Uses of DNA Profiling Tests?


Today’s community has civil & criminal uses for DNA profiling tests. DNA testing is extensively used in criminal cases, including Disaster Victim Identification and civil matters, such as determining kinship & establishing biological parentage. Moreover, researchers are also using DNA profiling to calculate the probability of genetic defects being passed on to future generations and detect genetic markers that contribute to disorders like diabetes, cancer, and Alzheimer’s.


As a medical application, it's used to match the tissues of a recipient & donor in organ transplantation cases. With the beginning of newer processes of profiling, the use of DNA in various fields will grow over time.


What are the Steps Involved in DNA Profiling Test?


DNA Profiling test is a systematic method starting with the sample collection of the involved parties. Blood, saliva, hair, and buccal swab samples are collected for DNA profiling. But a buccal swab is the most preferred option. First, the buccal swab sample is collected to rub against the wall of the cheeks. Next, the DNA will be cut for Short Tandem Repeats (STRs) analysis.


Instead, it uses Polymerase Chain Reaction (PCR) technology to create many copies of the STRs sequences.


After PCR makes many copies of sequences, electrophoresis separates different-sized molecules. They are then passed to laser sequencing, resulting in a distinctive DNA profile. But in the case of similar twins, the DNA profiles can be the same.


Applications of DNA Profiling Test


DNA profiling test is one of the most extensively used procedures for the accurate biological identification of a person. Furthermore, confirming genetic relationships among people and their alleged relatives is possible through the following types of tests.


Peace of Mind Biological Relationships: This test establishes the biological relationship for peace of mind between mother, father, grandparents, nephew, and niece.


Ancestry DNA Profiling Test:  Ancestry DNA tests can help to find extensive information about the ancestors. The ancestry DNA test can be done for different kinds of information, like


  • Paternal Lineage DNA Ancestry Test
  • Maternal Lineage DNA Ancestry Test
  • GPS Origins Ancestry Test


For Immigration: Another important use of a DNA profiling test is for immigration tests. Two parties are required for immigration DNA testing, i.e., the Petitioner and the Beneficiary. The petitioner and the beneficiary must be biologically related. 


If the primary documents are insufficient to verify that the involved parties are related, the immigration authority may reject the visa application. Therein, getting a DNA Immigration test beforehand helps avoid rejections.


Cell Line Authentication: This test is essential for various fields, such as drug & vaccine development, pharmaceutical research, etc. For e.g., they help in cross-contaminated, genetically drifted, and misidentified cell cases.


Organ Transplant DNA Test:  An individual needs a healthy organ from a deceased or living donor in case of organ failure. The Transplantation of Human Organs Act (THOA), 2014 states that a profiling test is required when the recipient & live donor are close relatives.


Why DNA Forensics Laboratory Pvt. Ltd. for Accurate DNA Profiling Test?


DNA Forensics Laboratory Pvt. Ltd. is among the best companies for accurate & reliable DNA profiling tests in India. The following are the key factors that make them one of the best DNA testing companies for DNA profiling tests in India:


  • The only company that provides legal DNA tests in India for honorable court
  • Regional collection representatives across India and abroad
  • Client confidentiality is their topmost priority
  • Fastest Turnaround time of 3-5 working days
  • Next-day and Same-day reporting options (T&C applied)
  • Availability of DNA testing kit online


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