Acid Sphingomyelinase Deficiency (ASMD) is a rare, inherited, autosomal recessive lysosomal storage disorder caused due to the deficiency of the enzyme sphingomyelin phosphodiesterase 1 required for breaking down sphingomyelin. It leads to accumulation of sphingomyelin substrate in cells of the brain and other vital organs. Signs and symptoms of ASMD include skeletal abnormalities, respiratory infections, liver dysfunction, and neurological abnormalities. The global ASMD market is driven by the increasing research in rare disease funding as well as rising disease awareness and diagnosis.
The acid sphingomyelinase deficiency (ASMD) market is estimated to be valued at USD 134.6 Mn in 2024 and is expected to reach USD 300 Mn by 2031, growing at a compound annual growth rate (CAGR) of 12.1% from 2024 to 2031.
Key players operating in the Acid Sphingomyelinase Deficiency (ASMD) market are Alexion Pharmaceuticals, Inc., Orchard Therapeutics and Green Cross Corp. Alexion Pharmaceuticals, Inc. is a leading player in the ASMD market with its enzyme replacement therapy Strensiq approved for the treatment of non-neurological manifestations of ASMD in children and adults.
The major opportunities in the Acid Sphingomyelinase Deficiency (ASMD) Market include the use of novel therapeutic approaches like gene therapy and stem cell therapy. Orchard Therapeutics is developing ex-vivo hematopoietic stem cell gene therapy OTL-200 for treating ASMD.
The ASMD market is also witnessing global expansion with key players focusing on raising disease awareness about ASMD in underdiagnosed regions. Alexion Pharmaceuticals is working with patient advocacy organizations globally to spread awareness about ASMD through initiatives like gene therapy educational programs.
Market Drivers -
Rising disease awareness and diagnosis: With initiatives from key pharmaceutical players and patient advocacy groups, the disease awareness about rare conditions like ASMD is increasing. This is resulting in improved diagnosis rates and growing patient pool globally.
Market Restrains -
High cost of gene and cell therapies: Novel therapeutic approaches for ASMD like gene and stem cell therapies are highly complex and expensive. This limits their widespread availability and adoption.
Segment Analysis
Acid Sphingomyelinase Deficiency (ASMD) Market is segmented on the basis of disease type, diagnosis and treatment. By disease type, the non-neurological forms of acid sphingomyelinase deficiency dominate the market currently. These types are characterized by lung and liver damages. These sub-segments hold around 60% of the overall market share owing to high prevalence and availability of treatment options. By diagnosis, genetic testing led the segment by identifying mutations in the SMPD1 gene responsible for acid sphingomyelinase deficiency. Over the forecast period, newborn screening is expected to be the fastest growing segment. By treatment, enzyme replacement therapy is the dominating sub-segment currently. Drugs like Eliglustat Tartrate (Cerdelga) hold over 50% market share for effectively managing symptoms in type I Gaucher disease patients.
Global Analysis
North America holds the largest share in the overall Acid Sphingomyelinase Deficiency (ASMD) Market owing to increasing research activities for developing novel treatment options. The region is expected to continue its dominance over the forecast period supported by high healthcare spending and presence of key pharmaceutical companies. Europe is the second largest market for ASMD attributed to rising government funding for rare disease research. Asia Pacific is poised to showcase fastest growth during forecast period driven by growing patient pool, improving healthcare facilities and rising medical tourism in the region. Developing nations like India and China are expected to be highly lucrative markets for ASMD in coming years.
Get this Report in Japanese Language: 酸性スフィンゴミエリナーゼ欠損症（ASMD）市場
Get this Report in Korean Language: 산성 스핑고미엘린 분해효소 결핍증(ASMD) 시장
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Global Acid Sphingomyelinase Deficiency Drug Market Research Report - Industry Analysis, Size, Share, Growth, Trends and Forecast Till 2027 – DecisionDatabases.comThe comprehensive value chain analysis of the market will assist in attaining better product differentiation, along with detailed understanding of the core competency of each activity involved.
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The segment analysis is useful in understanding the growth areas and probable opportunities of the market.Download Free Sample Report of Global Acid Sphingomyelinase Deficiency Drug Market @ https://www.decisiondatabases.com/contact/download-sample-23211The report also covers the complete competitive landscape of the global Acid Sphingomyelinase Deficiency Drug market with company profiles of key players such as: Genzyme CorporationLa Jolla Pharmaceutical CompanyMerck & Co., Inc.Okklo Life Sciences BVOrphazyme ApSThe detailed description of each has been included, with information in terms of H.Q, future capacities, key mergers & acquisitions, financial overview, partnerships, collaborations, new product launches, new product developments and other latest industrial developments.SEGMENTATIONS IN THE REPORT: By TypeLJPC-0712ML-SA1OKL-1014Olipudase AlfaOR-0005OthersBy ApplicationHospitalClinicOthersBy Geography:North America (NA) – US, Canada, and MexicoEurope (EU) – UK, Germany, France, Italy, Russia, Spain & Rest of EuropeAsia-Pacific (APAC) – China, India, Japan, South Korea, Australia & Rest of APACLatin America (LA) – Brazil, Argentina, Peru, Chile & Rest of Latin AmericaMiddle East and Africa (MEA) – Saudi Arabia, UAE, Israel, South AfricaBrowse the complete Global Acid Sphingomyelinase Deficiency Drug Market Research Report – Industry Analysis, Size, Share, Growth, Trends and Forecast Till 2027 @ https://www.decisiondatabases.com/ip/23211-acid-sphingomyelinase-deficiency-drug-market-report The Global Acid Sphingomyelinase Deficiency Drug Market has been exhibited in detail in the following chapters –Chapter 1 Acid Sphingomyelinase Deficiency Drug Market Preface Chapter 2 Executive SummaryChapter 3 Acid Sphingomyelinase Deficiency Drug Industry AnalysisChapter 4 Acid Sphingomyelinase Deficiency Drug Market Value Chain AnalysisChapter 5 Acid Sphingomyelinase Deficiency Drug Market Analysis By TypeChapter 6 Acid Sphingomyelinase Deficiency Drug Market Analysis By ApplicationChapter 7 Acid Sphingomyelinase Deficiency Drug Market Analysis By GeographyChapter 8 Competitive Landscape Of Acid Sphingomyelinase Deficiency Drug CompaniesChapter 9 Company Profiles Of Acid Sphingomyelinase Deficiency Drug IndustryPurchase the complete Global Acid Sphingomyelinase Deficiency Drug Market Research Report @ https://www.decisiondatabases.com/contact/buy-now-23211Other Reports by DecisionDatabases.com:Global Bronchitis Drug Market Research Report – Industry Analysis, Size, Share, Growth, Trends and Forecast Till 2027Global Herpes Zoste Drug Market Research Report – Industry Analysis, Size, Share, Growth, Trends and Forecast Till 2027Global Eosinophilic Esophagitis Drug Market Research Report – Industry Analysis, Size, Share, Growth, Trends and Forecast Till 2027About-Us:DecisionDatabases.com is a global business research reports provider, enriching decision makers and strategists with qualitative statistics.
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Acid lipase deficiency Market Research report provides a detailed analysis of of main manufactures and geographic regions,global market size, regional and country-level market size, segmentation market growth, market share, competitive Landscape, sales analysis, impact of domestic and global market players.
Acid lipase deficiency Market report includes definitions, classifications, applications, and industry chain structure, development trends, and key regions distributors analysis.The report also provides supply and demand Figures, revenue, revenue and shares.
value chain optimization, trade regulations, recent developments, opportunities analysis, strategic market growth analysis, product launches.Acid lipase deficiency market is expected to gain market growth in the forecast period of 2020 to 2027.
Data Bridge Market Research analyses the market is growing at a substantial CAGR in the above-mentioned research forecast period.Acid lipase deficiency market imparts a deep understanding of this industry vertical with key emphasis on the market dynamics and projected returns over the forecast period.Get Sample PDF of Acid lipase deficiency Market Report (including COVID19 Impact Analysis) @ https://www.databridgemarketresearch.com/request-a-sample/?dbmr=global-acid-lipase-deficiency-marketAcid lipase deficiencyAcid Lipase Deficiency Market Scope and Market Size:The acid lipase deficiency market is segmented of the basis of types, treatment, route of administration, end-user and distribution channel.
The growth among segments helps you analyze niche pockets of growth and strategies to approach the market and determine your core application areas and the difference in your target markets.Based on types, the acid lipase deficiency market is segmented into Wolman disease, Cholesteryl Ester Storage Disease (CESD) and others.The treatment segment for acid lipase deficiency market includes medication, hematopoietic stem cell transplantation, enzyme replacement therapy and others.On the basis of route of administration, acid lipase deficiency market is segmented into oral and parenteral.Key Players: Global Acid lipase deficiency MarketAlexion Pharmaceuticals, Inc, Synageva BioPharma Corp, ArmaGen, Bellicum Pharmaceuticals, Inc, Amicus Therapeutics, Inc. among other players domestic and global.
Acid Lipase Deficiency Market share data is available for Global, North America, Europe, Asia-Pacific, Middle East and Africa and South America separately.
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