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Polygala tenuifolia is a herb in the family Polygalaceae usually abbreviated P. tenuifolia and also known as Yuan zhi in traditional Chinese medicine.
It contains tenuifolin, senegenin and polygalacic acid.
It is one of the fundamental herbs in traditional Chinese medicine and acts as an expectorant and improves memory.It has not been proved that P. tenuifolia can improve memory spatial awareness and organization in humans but has been shown to have protective effects on the brain.
In healthy people, limited effects are seen while a slight increase in cognitive ability when supplementing Polygala tenuifolia in elderly people.
Rodent research studies that are assessing P.tenuifolia’s anti-amnesiac and adaptogen-like properties suggest that the herb can increase the level of compounds responsible for brain growth, like nerve growth factor (NGF) and brain-derived neurotrophic (BDNF).
No significant improvements in verbal fluency noted in elderly adults with memory complaints supplementing this herb.The recommended dosage is 100mg of an ethanolic extract called BT-11, three times a day, for a total daily dose of 300mg.