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How Stem Cell Therapy Can Treat Immune Disorders?

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Rachitaa Singh
How Stem Cell Therapy Can Treat Immune Disorders?

Immune disorders are usually treated with immune suppressants or immune-suppressing agents such as steroids, cyclosporine, methotrexate, and Remicade. This approach gives temporary relief but has long-term adverse effects on the body. Stem cell banking and subsequent usage can give a permanent cure for autoimmune diseases. Umbilical cord blood stem cells can heal damaged tissues and produce anti-inflammatory agents to heal the inflamed tissues. The best thing is that umbilical cord blood stem cells do not suppress the immune response of the body.


Furthermore, umbilical cord blood stem cells also produce T-regulatory cells, a type of immune cells whose main job is to protect the body from self-attacking the immune system. The body’s immune system is unable to recognize umbilical cord blood stem cells as foreign and therefore, they are never rejected by the body. Umbilical cord blood stem cells also proliferate more efficiently and are considered more effective than bone marrow stem cells. 


How Stem Cell Treats Immune Disorders

Umbilical cord blood is becoming the most promising ingredient to treat immune disorders. 

  • Cord blood stem cells intervene in immune suppression through immune modulation and suppression of inflammation.
  • Cord blood stem cells encourage the induction of regulatory Treg (T) cells.
  • Umbilical cord blood stem cells inhibit the propagation of Dendritic cells (DC).
  • Cord blood stem cells increase immune tolerance.
  • The presence of various secreted biomolecules including interleukin-10 (IL-10), transforming growth factor-β (TGF-β), nitric oxide (NO), indoleamine 2,3-dioxygenase (IDO), and prostaglandin E2 (PGE2) make stem cells an ideal therapeutic agent for long-term protection from autoimmunity.
  • Stem cells can be guided to become specific tissues that can be used to regenerate damaged and diseased tissues. 
  • Umbilical cord blood stem cells can treat diseases such as rheumatoid arthritis, juvenile idiopathic arthritis, systemic sclerosis, systemic lupus erythematosus, multiple sclerosis, Crohn's disease, autoimmune blood cytopenias, and type I diabetes mellitus.


Role of Stem Cell Banking in Treating Immune Disorders 


Newborn stem cell banking is an important step in the process of stem cell therapy. Auto-immune disorders are in many cases genetic. If your family has a history of immune disorders then you should consider newborn cord blood banking. The baby stem cell collection is a painless process that does not impact the mother and newborn in any way. Baby stem cell storage can be done with a cord blood bank. The benefits of stem cell banking are more than the cost of storage. Therefore, this should be considered a wise investment for the future of your offspring. Umbilical cord blood banking can help to treat more than 80+ diseases including genetic cancers and immune disorders.


Always ensure baby stem cell storage with a stem cell bank that has the proper infrastructure and certification. Newborn baby stem cell storage should be done preferably with a private stem cell bank where you can have access to the stem cells whenever required. To get the benefits of stem cell banking it is better to tie up with a hospital that allows umbilical cord blood collection.


Conclusion

The awareness regarding the benefits of cord blood banking is still less. Parents of the newborn should understand that stem cell preservation benefits not only helps the child whose stem cells have been preserved but also the entire extended family. Stem cell therapy is the treatment to look forward to for immune disorders.

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Rachitaa Singh
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