
Due to its use in a wide range of disciplines, including chemistry, biology, medicine, and the physical sciences, Microfluidics —the technique of fluid manipulation in channels with dimensions of tens of micrometers—has recently emerged as a noteworthy new area of study. The creation of lab-on-chip (LOC) devices, which are anticipated to bring about a revolution in the fields of chemistry and biology similar to what integrated circuits did for computing power, is a major driving force behind the field of microfluidic research.
Thanks to the incorporation of Microfluidics channels and active or passive components, including filters, valves, mixers, and many others, LOCs are microsystems that may combine entire biological or chemical laboratories on a single chip. Due to the high level of integration necessary in LOCs, there is a desire for new fabrication processes that can miniaturize a number of essential fluidic components in order to increase the compactness and functionality of these devices.
Microfluidics involves the manipulation of fluids at the microscale. It is a form of laboratory technology that enables scientists to work with a reduced sample size and at lower cost. As a result, scientists can conduct experiments with a higher degree of confidence and a reduced limit of detection. For example, when conducting a study, a scientist can perform a high throughput cell culture with a microfluidic lab-on-a-chip. This form of technology can be used to study single cell behavior, intercellular communication, and cell locomotion. These results are comparable to macroscopic culture assays.
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