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Citicoline - An Overview

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Dania Mercado
Citicoline - An Overview

Here's a brief overview of the benefits and risks of citicoline. The ingredient supports the cholinergic and dopaminergic systems. Read on for information on whether citicoline supplements can help treat alcohol and cannabis dependence. Also read on to learn whether it may reduce appetite in healthy adults or post-stroke patients. We've included the latest scientific research on citicoline, including clinical trials and a review of studies.


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Citicoline supports cholinergic and dopaminergic functions


A recent review of studies on citicoline suggests that it can support cholinergic and dopaminergic brain functions and reduce the severity of head injury. In addition, this neurotransmitter improves the health of nerve cells and mitochondria in the brain. This supplement is highly bioavailable and well absorbed, and its recommended dosage ranges from 500 to 2000 milligrams per day. This supplement has also been shown to improve the deteriorated axonal flow of dopamine in the brain.

It may be a treatment for alcohol and cannabis dependence


According to the study, the negative clinical implications of cannabis use in drug recovery are not yet well understood. This is a major concern given that patients in alcohol rehab often use other drugs. Further, research into the relationship between cannabis and other drugs is needed to understand how it affects recovery and relapse. There are also numerous benefits of cannabis, such as decreased risk of cancer, anxiety, depression, and insomnia.


It may reduce appetite in healthy adults


Researchers have now concluded that citicoline, a nutrient that helps regulate mood, may decrease appetite in healthy adults. In a study in mice, citicoline stimulated brain regions involved in regulating food responses and appetite, including the lateral orbitofrontal cortex and the insula. These changes in brain activity correlated with reduced ratings of food satisfaction. Further research is needed to determine whether citicoline has a beneficial effect on human appetite.

It may reduce appetite in post-stroke patients


There are some promising signs that citicoline might help reduce appetite in post-stroke patients. In a recent study, citicoline treatment was associated with better short-term and long-term functional outcomes. Its use also significantly reduced the burden of care, improved attention and executive function, and reduced weight gain. Although more studies are needed to assess these promising results, citicoline may be a promising treatment for stroke patients.


It may be a treatment for stroke recovery


A recent meta-analysis suggests that citicoline may help accelerate stroke recovery by improving neuroprotective and repair mechanisms in the brain. The study examined 12 randomized, placebo-controlled studies of citicoline, which found modest improvements in memory and behavior. Cognitive manifestations were also observed in patients with vascular cognitive impairment or dementia. It is possible that cognitive impairments are even more severe than physical disability. This study is the first to show that citicoline may help with stroke recovery.


It may be a treatment for eating disorders


A recent study on citicoline and eating disorders found that it can reduce the appetite. The researchers looked at functional MRIs to measure brain activity in response to food stimuli. After administering the drug to healthy adults, the subjects reported a decrease in appetite. Although the research is still in its preliminary stages, it may have important implications for eating disorders and appetite control. Read on to learn more about citicoline.


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It may be a treatment for schizophrenia


Researchers have discovered that citicoline can enhance the effects of conventional drugs for schizophrenia in a study of 66 patients. The drug showed improvements in negative symptoms of schizophrenia that are hard to treat with conventional treatments. In a similar study of 24 healthy adults, citicoline enhanced cognition by stimulating the activity of the nicotinic acetylcholine receptors, which are underactive in schizophrenia patients. Unfortunately, further research on this drug is necessary.


It may be a treatment for mild cognitive impairment


Citicoline has been studied in patients with Alzheimer disease, but its effectiveness in this population has been questioned. Previous clinical trials focused on a short duration of three months, and there has been no evidence to support the potential effects of longer-term administration. However, the recent IDEALE Study, a multicenter open-label study in elderly people, suggested that citicoline may improve cognition and be a treatment for mild cognitive impairment.

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Dania Mercado
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