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What are the Mechanisms of Action of Antiepileptic Drugs?

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What are the Mechanisms of Action of Antiepileptic Drugs?

The usage of statins is another illustration of a medicine that has been repurposed. Statins, which are frequently prescribed to treat high cholesterol, have also been found to have anti-epileptic effects. Refractory epilepsy, or epilepsy that does not respond to traditional Anti-Epileptic Drugs, has been found in recent research to be treatable with statins.


sIn addition to targeted medicines and drug repurposing, gene therapy is being investigated as a potential treatment option for epilepsy. In order to treat a patient's condition or cure a genetic abnormality, a functioning gene is inserted into their cells through the process of gene therapy. In relation to epilepsy, Each type of Anti-Epileptic Drugs works by a different mechanism of action, but they all aim to reduce the excitability of neurons in the brain and prevent seizures.


Here are some of the mechanisms of action of different types of AEDs:

  1. Sodium channel blockers: These AEDs work by blocking the influx of sodium ions into neurons, which can help to prevent the rapid firing of neurons that can lead to seizures.
  2. GABA enhancers: These AEDs work by increasing the amount of GABA in the brain, which can help to reduce neuronal excitability and prevent seizures.
  3. Calcium channel blockers: These Anti-Epileptic Drugs work by blocking the influx of calcium ions into neurons, which can reduce neuronal excitability and prevent seizures.
  4. Glutamate antagonists: These AEDs work by blocking the activity of glutamate receptors, which can prevent the excitatory effects of glutamate and reduce the likelihood of seizures.

 

Read More- http://latestcmiblogs.weebly.com/article/latest-innovations-in-anti-epileptic-drugs-advancements-in-seizure-management


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